The Whole-body Plethysmograph (WBP) is capable of measuring respiratory parameters of laboratory animals in conscious state and under unrestrained condition, such as respiratory rate, tide volume, Airway Hyperresponsiveness (AHR) test, etc.
Detailed Introduction WBP
The Whole-body Plethysmography (WBP) developed by Tow-Int Tech can measure respiratory parameters of laboratory animals in a conscious and unrestrained state, such as respiratory rate, tidal volume, and airway hyperresponsiveness (AHR) test.
Product Description WBP
The Whole-body Plethysmography (WBP) developed by Tow-Int Tech can measure respiratory parameters of laboratory animals in a conscious and unrestrained state, such as respiratory rate, tide volume, and airway hyperresponsiveness (AHR) test. WBP avoids the trauma of aerosol tube incisions and the effects of anesthesia, making the whole experimental process simpler. It is used to study the reaction of animal models to drugs and the pharmacology and toxicology of respiratory medications, especially suitable for the rapid initial screening tests of a large number of animal models for long-term follow-up research and repetitive screenings.
Product Features
No operation is required, and the instrument is easy to use
Multi-channel simultaneous monitoring
It can be used to study animal respiration in a natural state and conduct long-term follow-up experiments, which makes it suitable for the initial screening of drugs.
The drug aerosol atomization module is available
Automatic calibration function
There are drinking water and food ports for long-term continuous monitoring
Optional functions are available, for example, the measurements of ECG, blood pressure, body temperature, heart rate, and other vital signs, which can be combined with implantable telemetry equipment
Equipped with analysis software, data can be saved in Excel or TXT format
Test Parameters
Ti: Inspiratory Time (s)
Te: Expiratory Time (s)
PIF: Peak Inspiratory Flow (ml/s)
PEF: Peak Expiratory Flow (ml/s)
Volbal: Difference between Inspiratory/Expiratory Volume
F: Breath Frequency (breaths per minute)
Vt:Tidal Volume（ml）
Mv:Minute Ventilation（ml）
AV:Accumulated Volume（ml）
EF50: Mid-tidal Expiratory Flow
EIP: End-inspiratory Pause (Invasive Method)
EEP: End-expiatory Pause (Invasive Method)
TR: Relax Time
PenH: Enhanced Pause
Rpef: Ratio of Time to Peak Expiratory Flow
Applications
Researches on various respiratory diseases, such as asthma, pulmonary fibrosis, lung injury, ARDS, lung cancer, etc.
Safety pharmacology: the effect of drugs on the respiratory system
Sleep apnea: monitor animal hypopnea, obstructive apnea, etc.
Environmental Toxicology: The impact of environmental pollutants on animal respiration
Inhalation Toxicology: Toxic effects of toxic substances on the respiratory system
High altitude medicine: The influence of high altitude environment on the respiratory system
Other occasions where respiratory parameters need to be evaluated
- Aucune opération n'est requise et l'instrument est facile à utiliser
- Surveillance simultanée multicanal
- Il peut être utilisé pour étudier la respiration animale dans un état naturel et mener des expériences de suivi à long terme, ce qui le rend adapté au dépistage initial des médicaments
- Le module d'atomisation d'aérosol de médicament est disponible
- Fonction d'étalonnage automatique
- Apport d'eau et de nourriture pour une surveillance continue à long terme
- Des fonctions optionnelles sont disponibles, par exemple, les mesures de l'ECG, de la pression artérielle, de la température corporelle, de la fréquence cardiaque et d'autres signes vitaux, qui peuvent être combinées avec un équipement de télémétrie implantable
- Équipé d'un logiciel d'analyse, les données peuvent être enregistrées au format Excel ou TXT
| Référence | Ø transpondeur | Longueur transpondeur | Injecteur (Gauge) | Ø extérieur injecteur |
|---|---|---|---|---|
| TAM-S | 1,25 mm | 7 mm | 16 G | 1,6 mm |
| TAM-M | 1,40 mm | 8 mm | 15 G | 2 mm |
| TAM-L | 2,12 mm | 12 mm | 13 G | 2,5 mm |
Documentation Plestysmographe Intellibio.pdf
(562.84 KB)